Cyprotex ADME-Tox Solutions

Cyprotex enables and enhances the prediction of human exposure, clinical efficacy and toxicological outcome of a drug or chemical. By combining quality data from robust in vitro methods with contemporary in silico technology, we add value, context and relevance to the ADME-Tox data supplied to our partners in the pharmaceutical or chemical industries.

Cyprotex serves a number of different industries including the pharmaceutical and biotech, personal care and cosmetics, household products, and the chemical and agrochemical industries. We offer a comprehensive range of different services in the following areas:

TODO

Cyprotex eStore

Order our services online.

Visit the Cyprotex eStore

Cyprotex Unique Technologies

We offer a number of unique technologies either developed in-house or through our collaborators/partners.

TODO

eCiphr®Cardio

Synchronously beating iPS cell derived cardiomyocytes are monitored by high throughput microelectrode array (MEA) to measure whole cell electrophysiology and an ECG-like response. This technology provides a unique in vitro system for preclinical drug discovery, cardiotoxicity assessment and disease modelling.

Learn more
TODO

eCiphr®Neuro

Primary cortical neurons are monitored by high throughput microelectrode array (MEA). The cells recapitulate many features of neurons in vivo, and enable assessment of spiking rate, burst characteristics and synchrony. This technology provides a unique in vitro system for preclinical drug discovery, neurotoxicity assessment and disease modelling.

Learn more
TODO

CellCiphr® Premier

An extensive panel of toxicological endpoints are assessed in multiple cell types and at multiple time points using high content screening (HCS). By combining these endpoints with exposure levels (measured Cmax or predicted Cmax using Cloe® PK), the system delivers a sensitive and specific prediction of DILI (drug-induced liver injury).

Learn more
TODO

3D Microtissue & Multilayer Models

Logo Cyprotex white
Cyprotex enables and enhances the prediction of human exposure, clinical efficacy and toxicological outcome of a drug or chemical. By combining quality data from robust in vitro methods with contemporary in silico technology, we add value, context and relevance to the ADME-Tox data supplied to our partners in the pharmaceutical or chemical industries.