Drug Discovery

Molecular Design & Medicinal Chemistry

With a firm grasp on design, synthesis, analysis, and characterization, coupled with profound understanding of the biological and non-efficacy aspects of drug action, Drug Discovery Chemistry serves as the foundation for innovation and intellectual property protection, ultimately yielding significant value for our partners. At Evotec, we recognize the unique needs, capabilities, capacities, and philosophies of each partner, and thus we strive to offer flexible, innovative, and efficient chemistry solutions tailored to their specific requirements and goals.

Our Drug Discovery Chemistry team boasts a remarkable track record of success across diverse compound types, target classes, routes of administration, and disease areas. We are equipped to support our partners' programs at every phase of the chemical value stream, including hit creation, expansion, hit-to-lead, lead optimization, and development readiness. The scientific excellence and efficacy of all our chemistry endeavors are overseen by a leadership team with unparalleled levels of expertise, breadth of knowledge, and successful outcomes.

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Evotec's Chemistry Capabilities

Our comprehensive range of capabilities can be blended to provide needed or combined project solutions. These capabilities include:

  • Cutting-edge molecular design
  • Efficient and rapid synthetic execution
  • Route development and scale-up chemistry
  • Preparative chromatography services
  • Drug metabolism and pharmacokinetics (DMPK)
  • Solid state characterization and formulation support
  • Expert guidance on overall project strategy
  • Development and implementation of IP protection strategies
  • Effective project management

At Evotec, our chemistry groups are strategically co-located with DMPK and computational chemistry teams. This close proximity enables seamless communication and collaboration, allowing us to swiftly leverage combined experience and intellect when addressing interdisciplinary drug discovery challenges. This integrated approach facilitates rapid "design-make-test-analyze" cycles, particularly when clients require access to multiple activities to support their programs.

Contact Our Experts

Ashley Jarvis

Ashley Jarvis, PhD, FRSC

EVP Head of Drug Discovery Chemistry

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Evotec has the right technologies & disease understanding to meet our partners' evolving needs: a comprehensive disease knowledge at the molecular level, cutting-edge technologies & platforms to translate this expertise into effective precision medicines.