Evotec’s High-Throughput Protein Production and Data Generation Platform provides scalable, high-quality protein solutions to accelerate modern drug discovery. Using advanced expression systems and automated purification workflows, it rapidly delivers diverse protein formats across multiple hosts. Integrated screening technologies generate rich data for AI/ML model development, target validation, mechanism-of-action studies, and biologics developability. This LEAN-optimized platform ensures speed, reproducibility, and scientific depth, supporting precision-driven research and enabling the next breakthrough.
Evotec Expertise
Evotec’s high-throughput protein platform integrates in silico protein design with automated production workflows to deliver high-quality protein reagents quickly and cost-effectively. Proprietary technologies and deep expertise ensure consistent, reproducible results tailored to diverse research and development needs.
- Supports cell-free, E. coli, insect, yeast, and mammalian expression for rapid recombinant protein production
- Executes complex high-throughput workflows with specialist protein science expertise
- Bespoke reinforcement learning models to improve outcomes and reduce risk
- Provides automated, scalable purification for complexes, biologics, and membrane proteins
- Applies LEAN Six Sigma methods to ensure efficiency and reproducibility
- Integrates with Evotec assays to deliver functional, application-ready data
- Generates high-content data for AI/ML, interaction mapping, proteomics, and structural studies
High-throughput protein production and data generation workflow
Applications
- Supports rapid target expression and characterization for validation and pathway deconvolution
- Profiles compound effects to clarify mechanism of action and biological pathways
- Provides high-purity proteins for crystallography, cryo-EM, and NMR
- Supplies protein reagents for SPR, ITC, DSF, and other biophysical analyses
- Integrates protein and assay data to prioritize and optimize lead compounds
- Identifies protein complexes and interaction networks through interactome mapping
Featured Services
Frequently Asked Questions
Q: What is Evotec’s High-Throughput Protein Platform?
Evotec’s high-throughput protein platform is an industrialized, scalable system that rapidly produces high-quality protein reagents and rich, actionable data. It integrates advanced expression systems, automated purification, and proprietary screening technologies to accelerate drug discovery.
Q: Which expression systems are supported?
The platform supports cell-free IVTT, E. coli and other bacterial hosts, insect baculovirus systems, yeast, and mammalian cells to enable flexible and fast recombinant protein production.
Q: What types of proteins can be produced?
The system produces protein complexes, biologics, membrane proteins, and other difficult or high-value targets required for discovery and development programs.
Q: How is high-throughput protein purification handled?
Purification is delivered through automated, parallelized workflows supported by expert teams, smart construct design, and multi-parametric biochemical and biophysical analysis. Data are organized through a structured warehouse strategy, reinforced by AI/ML and predictive modeling to improve outcomes, reduce risk, and enable rapid DMTA cycles.
Q: What makes the platform high-throughput?
High-throughput capability is driven by LEAN Six Sigma–optimized processes, extensive automation across expression and purification, and parallel processing managed by a dedicated HT protein team.
Q: Can the platform integrate with assays?
Yes. The platform connects directly with Evotec’s assay technologies to generate high-quality functional and biophysical data tailored to specific research needs.
Q: What research applications does the platform support?
The platform supports target validation, mechanism-of-action studies, structural biology workflows, biophysical assays, lead compound prioritization, and interactome mapping to define protein interactions and pathways.
Q: What sets Evotec’s platform apart?
Evotec combines in silico protein design, high-throughput production, proprietary technologies, and deep domain expertise to deliver speed, reproducibility, and scientific depth across protein science programs.
