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1 Contributed equally to this work with: Sebastian K. Wandinger, Idoya Lahortiga
2 Evotec (München) GmbH, Martinsried, Germany
3 VIB Center for the Biology of Disease, Leuven, Belgium, KU Leuven, Center for Human Genetics, Leuven, Belgium
4 Oncology Drug Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium