3D Microtissue & Multilayer Models

Cyprotex, a wholly owned subsidiary of Evotec, has extensive experience in developing screening techniques using 3D microtissue, spheroid and multi-layer cellular models.

3D cellular models have many advantages:

  • 3D cellular models are amenable to long term repeat dose studies which are not possible using 2D systems.
  • 3D cellular models closely mimic native tissues and have the benefit of cell-to-cell interactions and displaying their in vivo physiology.
  • Most 3D models are amenable to high content imaging as well as biochemical endpoints.

3D Microtissue, Spheroid & Multi-layer Cell Model Services

We can offer:

Other commercially available 3D models can be implemented into Cyprotex’s workflow, contact us with your requirements.


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Sam Bevan

Sam Bevan

Principal Scientist

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Cyprotex enables and enhances the prediction of human exposure, clinical efficacy and toxicological outcome of a drug or chemical. By combining quality data from robust in vitro methods with contemporary in silico technology, we add value, context and relevance to the ADME-Tox data supplied to our partners in the pharmaceutical or chemical industries.