Summary

Evotec is a recognised leader in pharmaceutical research and offers a comprehensive range of capabilities to support drug design, discovery and development. High quality protein for biochemical assay and structural biology studies is essential for any drug discovery project. A challenging target may require multiple optimisation rounds to obtain soluble, pure and active protein. Here we present diverse methodologies to overcome those challenges through construct design, vector and host selection. We also present the rigorous control methods necessary to ensure the high quality of protein produced for a variety of applications.

_{1 Evotec (UK) Ltd. Abingdon, United Kingdom}

_{2 Evotec (München) GmbH, Munich, Germany}