About the Webinar

Watch our webinar to see how Evotec has developed an innovative strategy for identifying and validating covalent hits using high throughput mass spectrometry and chemoproteomic profiling.

In this webinar, our expert speakers, Julien Parra PhD (Senior Research Scientist, High Throughput Biology and Screening) and Violette Gautier PhD (Research Scientist, Proteomics), explore the latest technologies in covalent drug discovery.

Key Insights

  • Covalent inhibitors positioning and their unique benefits in modern drug discovery
  • How high throughput mass spectrometry accelerates covalent hit ID
  • Site specific analysis using peptide mapping and intact protein mass spectrometry
  • Advanced chemoproteomics strategies for hit validation

Meet the Speakers:

Julien Parra Ph D

Julien Parra PhD

Senior Research Scientist, High Throughput Biology & Screening

Latest update: December 2025

Biography

Currently serving as a senior research scientist in the high-throughput biology and screening team at Evotec in Toulouse, Dr. Julien Parra is a highly experienced mass spectrometry specialist with over a decade of experience in analytical chemistry, proteomics and structural biology. Julien earned his PhD in analytical chemistry from the Université Évry Paris-Saclay and later joined the Institute of Pharmacology and Structural Biology as a postdoctoral researcher. His work is characterized by a deep understanding of protein chemistry, a strong command of mass spectrometry instrumentation and a passion for translating complex data into biological insights.

Violette Gautier Ph D

Violette Gautier PhD

Research Scientist, Proteomics

Latest update: December 2025

Biography

Dr. Violette Gautier is a proteomics research scientist with over fifteen years of experience in proteomics, including more than nine years in the pharmaceutical industry. At Evotec, she specializes in chemoproteomics approaches such as activity-based protein profiling and cysteine proteomics profiling. She contributes to covalent drug discovery programs by developing and applying chemoproteomic workflows that support key stages of compound progression - from target identification and ligand library screening to cellular target engagement and selectivity profiling. Violette earned her PhD in structural and functional biology from Toulouse III University and completed her postdoctoral research at Utrecht University. Both focused on advanced proteomic strategies to investigate protein networks, cellular mechanisms and post-translational modifications.

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