This Webinar, hosted by DDW and supported by Evotec, explores cutting-edge LC-MS-based bioanalytical approaches tailored for the quantitative analysis of therapeutic proteins, such as monoclonal antibodies (mAbs), antibody-drug conjugates (ADCs), fusion protein biomarkers, and oligonucleotides in biological fluids and tissues. You will learn about:
- LC-MS method development and quantification strategies
- Intact, hybrid, and direct digestion for therapeutic proteins
- ADC stability linker strategies • ADC PK assays applied to micro-sampling
- Oligonucleotide quantification in plasma and tissues
- Case studies
Meet the Presenter
Marcho Michi
Senior Research Leader
Dr. Michi brings more than 20 years of experience in the field, with extensive expertise in both regulated and discovery bioanalysis, including the implementation of innovative lean processes and advanced analytical technologies. In recent years, he has led the development and execution of Evotec’s DMPK bioanalytical strategy for biologics across multiple sites. He also oversees bioanalytical activities for the DMPK division at the company’s Italian location.
This webinar is moderated by Dino Montanari, VP Head of PK/PD, Modelling & Simulation at Evotec.
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This webinar was hosted by DDW and supported by Evotec.
