BTS British Toxicology Society Annual Congress 2025

Using iPSC Cardiomyocytes and Transcriptomics (RNA-sequencing) for Cardiotoxicity Risk Assessment and Mechanistic Insight

P. Walker¹, J. Eakins¹, C. Bruhn², S. Llewellyn¹, B.Park¹, M. Fernandes dos Reis², & R. Rex² 

^{1 Cyprotex Discovery Ltd, Alderley Park, Macclesfield, Cheshire, SK10 4TG, UK; Poster number 46; 2 Evotec International GmbH, Marie-Curie-Str. 7, Göttingen, D-37079, Germany)}

The Application of New Approach Methodologies as an Integrated Safety Strategy to De-Risk Drug-Induced Liver Injury in Drug Discovery

Julie Eakins¹, Benjamin Park¹, Samantha Bevan¹, Micael Fernandes dos Reis², & Rene Rex² & Paul Walker¹

^{1 Cyprotex Discovery Ltd, Alderley Park, Macclesfield, Cheshire, SK10 4TG, UK; Poster number 46; 2 Evotec International GmbH, Marie-Curie-Str. 7, Göttingen, D-37079, Germany)}