A Glimpse into our PCD Facility


At Evotec, our dedicated team of pathologists and histology scientists, supported by renowned external consultants, collaborates to assess drug candidate safety and efficacy. Our experts bring decades of experience in laboratory animal pathology and histotechnology, aiding drug development from discovery to safety studies. We specialize in toxicological assessments, biomarker identification, and maintaining rigorous quality standards. Join us in reshaping medicine through groundbreaking research and innovation. Explore our services and collaborate for a healthier future.

Get To Know Our Pathology Team

Welcome to the Pathology Department at our state-of-the-art Preclinical Development Facility! We take pride in being at the forefront of innovative research, playing an essential role in advancing scientific understanding in drug development.

Our dedicated team of anatomic pathologists, clinical pathologists and histology scientists at Evotec, alongside our trusted, internationally recognized external consultant partners, work collaboratively to provide comprehensive insight into the safety and efficacy of potential drug candidates.

Our pathologists hold a degree in Veterinary Medicine, a PhD and internationally recognized pathology qualifications such as DACVP and DiplECVP. They specialize in the microscopic examination of tissues, with up to 25 years of experience in laboratory animal pathology, spanning the entire drug development process, from discovery/lead candidate optimization to chronic preclinical safety studies. The histology team is composed of a group of histology scientists who hold an academic degree and specialized histo-technology training, combined with a up to 30-years' experience.

Evotec Pathology unit is principally dedicated to the support of rigorous toxicological assessments aimed at evaluating the potential adverse effects of compounds in multiple species (rodents and non-rodents), but is also providing expertise into the conduct of investigative safety studies to mitigate attrition issues and the validation and histopathological characterization of animal models of human disease and phenotyping studies. Through molecular techniques, our anatomic and clinical pathologists help with the identification and validation of specific biomarkers in support to the development of targeted therapies and personalized medicine.

Maintaining the highest standards of quality and accuracy is non-negotiable for us. Our laboratory adheres to strict regulatory guidelines, employing robust quality control measures at every stage of analysis. GLP and international regulatory standards are applied to all pathology activities to meet the requirements for developing drug products worldwide.

We invite you to explore the dynamic world of pathology within our Preclinical Development. Witness the synergy between a strong tradition and expertise in a regulatory environment with cutting-edge technology and scientific build as we transform the landscape of medicine through groundbreaking research and innovation.

Contact us to learn more about our services, collaborate on research initiatives, or schedule a facility tour. Together, let's pave the way for a healthier tomorrow through the power of pathology.

Automatic Tissues Processor

Our Pathology Services & Capabilities

  • Necropsies with tissue collection, organ weight and macroscopic data recording
  • Tissue trimming and histological slide preparation according to international requirements, with routine hematoxylin and eosin (H&E), plus a broad range of histochemical and immuno-histochemical techniques
  • Comprehensive pathology narrative reports inclusive of correlations with other study data, plus integration into the study report (GLP and non-GLP up to 9 months duration).
  • Clinical pathology data interpretation, expertise in biomarker set-up and validation
  • Peer review - quick and cost-effective internal peer review process
  • Consultancy services. Our pathologists are readily available to provide expert consultations, aiding in study design, data interpretation, and regulatory compliance.
  • Slide scanning with state-of-the-art high throughput digital slide scanners and remote data sharing
  • Digital Pathology: we utilize digital pathology platforms and software, including AI-assisted, to provide quantitative assessment of specific morphological endpoints (e.g. immunohistochemistry quantitative analysis). We actively partner with academic institutions and research organizations to develop customized image analysis solutions
  • Tissue cross reactivity studies, from the beginning to the end (GLP and non-GLP)
  • Neurotoxicity (extensive brain trimming, implementation of best practice for peripheral nervous system evaluation in rodent and non-rodent species and neurovacuolation studies, Olney’s test)
  • Transmission electron microscopy, from grid preparation to interpretation of ultrastructural changes Pathology activities are part of fully-integrated packages, including all aspects of drug development at a single site (INDiGO)

Contact Our Experts

Giovanni Pellegrini

Giovanni Pellegrini, DVM, PhD, Dipl ECVP

Head of Pathology

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Evotec has the right technologies & disease understanding to meet our partners' evolving needs: a comprehensive disease knowledge at the molecular level, cutting-edge technologies & platforms to translate this expertise into effective precision medicines.