Pipeline

Constantly growing pipeline of product opportunities

EVT Innovate develops drug discovery programmes and assets, both internally or through academic collaborations. Evotec seeks to partner these into collaborations in return for upfront payments, ongoing research payments and significant financial upside through milestones and royalties.

 

Pipeline of product opportunities (including EVT Execute programmes)

Programme
Therapeutic area/Indication
Partner
Status
EVT201
CNS - Insomnia (GABA-A)
JingXin
Phase III
ND
Infectious Disease (Antibody)
SK bioscience
Phase III
CT7001
Oncology (CDK7)
Carrick
Phase II
BAY2395840
Diabetic Neuropathic Pain (BDKRB1)
Bayer
Phase II
EVT401
Immunology & Inflammation (P2X7)
CONBA Group
Phase I
BAY2395840
Gynaecology
Bayer
Phase I
BAY2328065
Gynaecology
Bayer
Phase I
XP-105
Oncology (mTORC1/2)
Xynomic Pharmaceuticals
Phase I
TPM203
Pemphigus Vulgaris (ND)
Topas Therapeutics
Phase I
CNTX 6016
Pain (CB2)
Centrexion
Phase I
EVT894
Chikungunya (ND)
Sanofi/NIH
Phase I
EXS21546
Oncology (A2a)
Exscientia
Phase I
EVT801
Oncology (VEGFR3)
Kazia Therapeutics
Phase I
EVT8683
Neurodegeneration (elF2b)
Bristol Myers Squibb
Phase I
APN411
Oncology - Immunotherapy (ND)
Sanofi/Apeiron
Pre-clinical
Encaps-iBeta
Diabetes - beta cell replacement therapy
Sernova
Pre-clinical
EVT075
Covid-19/ HBV (ND)
Currently unpartnered
Pre-clinical
GLPGxxx
Fibrosis (ND)
Galapagos
Pre-clinical
BAYxxx
Nephrology (ND)
Bayer
Pre-clinical
TPM501
Celiac disease
Topas Therapeutics
Pre-clinical
Various
CNS, Metabolic, Pain ......
>10 further programmes
Pre-clinical
Various
Nephrology
Bayer
Discovery
Various
Immunology & Inflammation
UCB
Discovery
Various
Neurodegeneration
Bristol Myers Squibb
Discovery
Various
Oncology - solid tumours
Bristol Myers Squibb
Discovery
Various
Immunology & Inflammation - Tissue Fibrosis
Pfizer
Discovery
Various
Polycystic Ovary Syndrome 
Bayer/Celmatix
Discovery
Various
Nephrology
Novo Nordisk
Discovery
Various
Nephrology
Chinook Therapeutics
Discovery
Various
Various
Takeda
Discovery
ND
Oncology
Breakpoint Therapeutics
Discovery
ND
Anti-infectives
Forge Therapeutics
Discovery
ND
FSHD
Facio Therapies
Discovery
INDY inhibitor
Metabolic
Eternygen
Discovery
ND
Fibrotic disease
Fibrocor/Galapagos
Discovery
ND
Gaucher
Centogene
Discovery
Various
Various
Topas Therapeutics
Discovery
ND
Heart failure
UKE
Discovery
Various
Various

LAB282 / LAB150 / LAB10x / Autobahn Labs / beLAB2122 / beLAB1407 / Danube Labs

Discovery
Various
Anti-infectives
>5 programmes
Discovery
Various
Internal: Oncology, CNS, Metabolic, Pain & Inflammtion, Immunology and Anti-invectives
>40 further programmes
Discovery
Programme EVT201
Therapeutic area/Indication CNS - Insomnia (GABA-A)
Partner JingXin
Status Phase III
Programme ND
Therapeutic area/Indication Infectious Disease (Antibody)
Partner SK bioscience
Status Phase III
Programme CT7001
Therapeutic area/Indication Oncology (CDK7)
Partner Carrick
Status Phase II
Programme BAY2395840
Therapeutic area/Indication Diabetic Neuropathic Pain (BDKRB1)
Partner Bayer
Status Phase II
Programme EVT401
Therapeutic area/Indication Immunology & Inflammation (P2X7)
Partner CONBA Group
Status Phase I
Programme BAY2395840
Therapeutic area/Indication Gynaecology
Partner Bayer
Status Phase I
Programme BAY2328065
Therapeutic area/Indication Gynaecology
Partner Bayer
Status Phase I
Programme XP-105
Therapeutic area/Indication Oncology (mTORC1/2)
Partner Xynomic Pharmaceuticals
Status Phase I
Programme TPM203
Therapeutic area/Indication Pemphigus Vulgaris (ND)
Partner Topas Therapeutics
Status Phase I
Programme CNTX 6016
Therapeutic area/Indication Pain (CB2)
Partner Centrexion
Status Phase I
Programme EVT894
Therapeutic area/Indication Chikungunya (ND)
Partner Sanofi/NIH
Status Phase I
Programme EXS21546
Therapeutic area/Indication Oncology (A2a)
Partner Exscientia
Status Phase I
Programme EVT801
Therapeutic area/Indication Oncology (VEGFR3)
Partner Kazia Therapeutics
Status Phase I
Programme EVT8683
Therapeutic area/Indication Neurodegeneration (elF2b)
Partner Bristol Myers Squibb
Status Phase I
Programme APN411
Therapeutic area/Indication Oncology - Immunotherapy (ND)
Partner Sanofi/Apeiron
Status Pre-clinical
Programme Encaps-iBeta
Therapeutic area/Indication Diabetes - beta cell replacement therapy
Partner Sernova
Status Pre-clinical
Programme EVT075
Therapeutic area/Indication Covid-19/ HBV (ND)
Partner Currently unpartnered
Status Pre-clinical
Programme GLPGxxx
Therapeutic area/Indication Fibrosis (ND)
Partner Galapagos
Status Pre-clinical
Programme BAYxxx
Therapeutic area/Indication Nephrology (ND)
Partner Bayer
Status Pre-clinical
Programme TPM501
Therapeutic area/Indication Celiac disease
Partner Topas Therapeutics
Status Pre-clinical
Programme Various
Therapeutic area/Indication CNS, Metabolic, Pain ......
Partner >10 further programmes
Status Pre-clinical
Programme Various
Therapeutic area/Indication Nephrology
Partner Bayer
Status Discovery
Programme Various
Therapeutic area/Indication Immunology & Inflammation
Partner UCB
Status Discovery
Programme Various
Therapeutic area/Indication Neurodegeneration
Partner Bristol Myers Squibb
Status Discovery
Programme Various
Therapeutic area/Indication Oncology - solid tumours
Partner Bristol Myers Squibb
Status Discovery
Programme Various
Therapeutic area/Indication Immunology & Inflammation - Tissue Fibrosis
Partner Pfizer
Status Discovery
Programme Various
Therapeutic area/Indication Polycystic Ovary Syndrome 
Partner Bayer/Celmatix
Status Discovery
Programme Various
Therapeutic area/Indication Nephrology
Partner Novo Nordisk
Status Discovery
Programme Various
Therapeutic area/Indication Nephrology
Partner Chinook Therapeutics
Status Discovery
Programme Various
Therapeutic area/Indication Various
Partner Takeda
Status Discovery
Programme ND
Therapeutic area/Indication Oncology
Partner Breakpoint Therapeutics
Status Discovery
Programme ND
Therapeutic area/Indication Anti-infectives
Partner Forge Therapeutics
Status Discovery
Programme ND
Therapeutic area/Indication FSHD
Partner Facio Therapies
Status Discovery
Programme INDY inhibitor
Therapeutic area/Indication Metabolic
Partner Eternygen
Status Discovery
Programme ND
Therapeutic area/Indication Fibrotic disease
Partner Fibrocor/Galapagos
Status Discovery
Programme ND
Therapeutic area/Indication Gaucher
Partner Centogene
Status Discovery
Programme Various
Therapeutic area/Indication Various
Partner Topas Therapeutics
Status Discovery
Programme ND
Therapeutic area/Indication Heart failure
Partner UKE
Status Discovery
Programme Various
Therapeutic area/Indication Various
Partner

LAB282 / LAB150 / LAB10x / Autobahn Labs / beLAB2122 / beLAB1407 / Danube Labs

Status Discovery
Programme Various
Therapeutic area/Indication Anti-infectives
Partner >5 programmes
Status Discovery
Programme Various
Therapeutic area/Indication Internal: Oncology, CNS, Metabolic, Pain & Inflammtion, Immunology and Anti-invectives
Partner >40 further programmes
Status Discovery

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