EVOcells - from cells to therapies
CELL THERAPY – NEXT GENERATION MODALITY TO REVOLUTIONIsE DISEASE TREATMENT
Cell therapy is a fast-growing and highly promising field of biomedical research that plays an important role in the development of novel therapeutics. This approach uses a cell product with therapeutic effect, derived from living cells that are cultivated outside of the body before being injected or transplanted. Cell therapy offers exceptional opportunities and has the potential to achieve substantial disease-modifying effects within a single treatment, or to even completely cure diseases.
The truly curative treatment potential of cell therapy involves:
- Replacing declining function of diseased tissue and/or stimulation of regeneration
- Stimulating cell-mediated immunity
- Broad applicability to diseases of pancreas, heart, muscle, immune system and others
A WORLD-CLASS INFRASTRUCTURE TO DELIVER OFF-THE-SHELF, ALLOGENEIC CELL THERAPY PRODUCTS TO PATIENTS
Functioning cells for cell therapy can be obtained from different sources: either from a healthy donor, from a patient, or from stem cells, including induced pluripotent stem cells (“iPSC”). Using iPSC for cell therapy has opened up stem cells as an almost unlimited source of consistent-quality material. Thus, manufacturing cell products from a single iPSC line overcomes many of the limitations when using such as scalability and reproducibility of manufacturing.
Therefore, EVOcells, Evotec’s approach to cell therapy, leverages iPSC-based technology and combines this with Evotec’s drug discovery and development platforms. Evotec’s industry leading iPSC platform has been developed over the last years to industrialise the use of iPSC technology in terms of throughput, reproducibility and robustness for applications both in drug screening as well as in next generation off-the-shelf allogeneic cell therapies.
