Addressing your complex formulation issues fast from an early stage
Evotec’s pre –clinical formulation team can assist you in developing "phase-appropriate" formulations tailored to your compound properties.
Poor solubility/ low bioavailability are significant issues during drug development. It is reported that up to 75% of compounds currently under development are poorly water-soluble, with this figure rising to 90% for new chemical entities. This is of concern because solubility issues can compromise the developability of compounds, resulting in project delays and ultimately increase the overall cost of a project. Therefore, it is important to understand and address bioavailability issues early with "phase-appropriate" formulation strategies.
A fast, cost effective and flexible approach in each stage of development focusing in meeting the project needs:
- Evotec has considerable expertise in formulation and can expedite early phase formulation development from discovery to clinic
- Evotec’s early formulation team can tackle your formulation problems fast, in support of pre-clinical testing using small amounts of compound
- This dedicated and responsive team of pre-clinical formulation scientists has an in-depth knowledge of a wide range of formulation capabilities and expertise to support your project, ranging from simple to complex, bio-enhanced approaches
- The team works in synergy with Material Science/ DMPK investigators and toxicologists to design an effective formulation screening programme that can quickly solve your formulation problems
How do we work with your team?
We work with your team using 4 very simple steps to improve the outcome of your pre-clinical studies: