Design and apply innovative technologies to dramatically expand global access to biotherapeutics
Just – Evotec Biologics is an integrated design company focused on technologies that accelerate the discovery and development of high quality biotherapeutics and substantially reduce their manufacturing cost.
At our core is a deeply experienced team with an understanding of the challenges that block access to these important therapeutics, and a solution we call J.DESIGN.
SOLUTIONS - APPLYING DEEP INDUSTRY KNOWLEDGE AND DATA-DRIVEN SOLUTIONS TO BIOLOGICS DESIGN AND MANUFACTURING
J.DESIGN is our AI-driven and fully integrated technology platform for biotherapeutic development.
Utilising J.DESIGN we are able to accelerate development and provide superior manufacturing process control for higher quality molecules at the lowest possible cost. Leveraging J.DESIGN we can partner anywhere in the continuum of biologics drug development.
J.DISCOVERY™ Services – for the identification of superior antibody therapeutics
- In vitro antibody production with our humanoid antibody library, J.HALSM. Antibodies designed and sequence biased for broad efficacy, superior developability and manufacturability features
- Fully established in vivo antibody generation and discovery with a proven and validated platform
- Target validation, functional assays, biophysical characterisation, post-translational modification analysis by mass spec
J.MD™ - MOLECULE DESIGN
A suite of research and development services that utilise Abacus™ and other predictive computational tools. Antibodies from animals or people are improved for manufacturing and formulation.
- Parental antibody sequences are humanised and optimised to enhance manufacturability and stability
- Abacus™ is an in-house suite of proprietary computational tools that enable prediction of the best molecules and conditions for development
- Product candidates are evaluated using assays that indicate how well a molecule is expressed, purified and formulated
JP3® - PROCESS AND PRODUCT DESIGN
Leverages high-throughput technology to rapidly deliver robust manufacturing processes.
- Proprietary cell lines, vectors, and media with process options for continuous, intensified fed-batch, and fed-batch
- Chromatography, filtration, and viral clearance capabilities for removal of impurities
- Biophysical and formulation development tools for defining optimal storage stability
- High resolution analytical capabilities, including mass spectrometry based multi-attribute method (MAM)
J.POD® - MANUFACTURING AND PLANT DESIGN
Our J.POD® research and development services offer the client unique solutions for the design of flexible, deployable technologies and facilities needed to improve speed and cost-effectiveness of manufacturing, while never compromising quality.