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ALTANA Pharma Selects Evotec as Partner for a Kinase Lead Identification Program
Evotec is collaborating with ALTANA Pharma AG to advance the discovery on one of their kinase targets. Applying Evotec's drug discovery engine from target to clinic, the companies aim to identify and optimize novel lead compounds that interact with the target in the research program.
In this research collaboration with ALTANA, Evotec will develop the kinase assay, screen it against Evotec's library of over 250,000 drug-like compounds using its proprietary high throughput screening technology EVOscreen® and characterise the hits generated. In the subsequent medicinal chemistry program, the hits will be further optimized in terms of their potency, selectivity, ADMET and pharmacokinetic profile to identify lead compounds to advance towards the clinic.
"Pharmaceutical research collaborations with competent external partners are important to supplement in-house drug discovery knowledge and experience. The relationship between Altana and Evotec has developed since 2001. By setting up highly innovative assay systems in a remarkably short time frame Evotec has already proven to us to be an excellent drug discovery partner and we are looking forward to expand our partnership."
Dr. Ulrich Thibaut, Vice President Discovery Research, ALTANA Pharma