World class biology and chemistry expertise is provided for all major biological target classes including GPCRs, kinases, ion channels, proteases, NHRs and protein-protein interactions. The offering is further enhanced by our drug discovery platform via an unrivaled range of solutions from ligand design to delivery of clinical candidates.
Numerous projects have matured from reagent production, assay development and screening into hit-to-lead and lead optimization medicinal chemistry, structural biology and computational chemistry. Many have yielded compounds for preclinical and clinical evaluation.
A broad and powerful platform of functional and binding assays for primary and secondary screening, as well as focused screening compound collections for enhanced hit-identification are also provided.