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Proteomics and Biomarker Discovery

Evotec Munich`s capabilities comprise a unique combination of innovative technologies:

  • Cellular Target Profiling® reveals the molecular targets of small molecule compounds with unknown mode-of-action on a proteome-wide basis and facilitates successful target deconvolution and off-target analysis early in the discovery and development process.
  •  KinAffinity® determines the cellular selectivity of kinase inhibitors, which represent the most important class of targeted cancer drugs.
  •  PhosphoScout® provides valuable knowledge about a drug’s in vivo mode-of-action and drug response.  
  •  Epigenetics Target Profiling® reliably analyzes the selectivity of epigenetic drugs in cells and tissue, supporting drug discovery in one of the fastest growing therapeutic target areas.
  •   Epigenomics Analyses monitor posttranslational modifications in vivo, revealing a drug’s influence on global posttranslational modification patterns.
  •  Quantitative Proteomics Analyses identify and quantify proteins in a global and unbiased manner, highlighting how cellular processes affect the current physiological state of the cell.

Projects are customized and adapted to meet the expectations of Evotec’s partners; for more information please contact us at proteomics@evotec.com

Proteomics and Biomarker Discovery

Cellular Target Profiling®

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KinAffinity®

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PhosphoScout®

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Epigenetics Target Profiling®

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Epigenomics Analyses

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Quantitative Proteomics Analyses

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Publications

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