Posters 2010

2010	Title	Meeting
	Hierarchical GPCR modelling; application to Bradykinin 1 Receptor (B1R), Histamine 3 (H3) receptor and Melanin-Concentrating Hormone receptor 1 (MCHR1) Richard J Law et al	High Resolution Neuropharmacology meeting, 10-12 Nov, San Diego, USA
	Selective blockade of NR2B subunit containing NMDA receptors enhances AMPA receptor-mediated EPSPs and sub-maximal LTP in hippocampal CA1 pyramidal neurons through disinhibitory effects John Kemp et al	4th annual meeting Neuroscience 2010, 13-17 Nov, San Diego, USA
	Pharmacological characterisation of EVT 101, a novel potent and orally acting NR2B subtype selective NMDA antagonist Andrea Cesura et al	4th annual meeting Neuroscience 2010, 13-17 Nov, San Diego, USA
	Protein phosphotase 1E (PPM1E), up-regulated in early Alzheimer's disease Braak stages, affects dendritic spine morphognesis Heinz von der Kammer et al	4th annual meeting Neuroscience 2010, 13-17 Nov, San Diego, USA
	Modulation of NMDA and alpha7 nicotinic ACh receptor by tryptophan metabolites Ioana Neagoe et al	Discovery on Target, 2-4 Nov, Boston, USA
	An orally bioavailable and efficacious mGlu₄receptor positive allosteric modulator with potential for the treatment of Parkinson's disease Stephen East et al	3rd RSC/SCI Symposium on GPCRs in Medicinal Chemistry, 20-22 Sept, Oss, Netherlands
	New steroidal mineralcorticoid antagonists Christopher Yarnold et al	EFMC-ISMC 2010,21st International Symposium on Medicinal Chemistry, 5-9 Sept, Brussels, Belgium
	The combination of high content screening and stem cells for the treatment of neurodegenerative disorders York Rudhard et al	Stem Cells Europe, 24-25 Aug, Edingburgh, Scotland
	Phthalazinone pyrazoles as potent, selective and orally bio-available inhibitors of Aurora-A kinase Michael Prime et al	ACS conference, 22-26 Aug, Boston, USA
	Conformational change of mammalian serine racemase upon inhibitor binding Myron Smith et al	ACA Inc 2010 Annual Meeting, 24-29 July, Chicago, USA
	Comparison of large chemical libraries using unsupervised classification techniques Alexander Böcker	5th Joint Sheffield Conference on Chemoinformatics, 13-15 July, Sheffield, UK
	Identification of novel, small molecule Bradykinin B1 antagonists with oral activity in rodent models of pain and inflammation David Hallett et al	World Pharma Congress, 14-16 June, Philadelphia, USA
	GPCR modelling from sequence to 3D structure, application on bradykinin 1 (B1) and histamine 3 (H3) receptors Sandeep Pal et al	GPCR Congress, 9-10 June, Montreux, Switzerland
	Development of a KNIME workflow using JChem nodes for Evotec's compound library enhancement program Michael P Mazanetz et al	ChemAxon User Group, 18-20 May, Budapest, Hungary
	An assay platform for mechanistic validation of small molecule inhibitors during lead compound identification and optimisation Florian Krieger et al	EMBO Hamburg, 5-7 May, Hamburg, Germany
	Identification of fragment inhibitors of phosphodiesterase 10a (PDE10a) Isabel Moraes et al	Keystone Symposia in Small Molecule Drug Discovery, 20-25 Apr, Whistler, Canada
	Strategies for combining high throughput screens with orthogonal readouts for hit validation against viral protein-protein interaction targets Joachim Krämer et al	Keystone Symposia in Small Molecule Drug Discovery, 20-25 Apr, Whistler, Canada
	Electrophysiological cardiac safety assessment in drug discovery and development Clemens Möller et al	SBS 16th Annual Conference, 11-15 Apr, Phoenix, USA
	Fragment-based drug discovery by NMR – The advantages of isotope-labelling Jan Kahmann et al	MedChem Europe, 8-9 Apr, Munich, Germany
	Novel heterocyclic-azepine analogues as potent and selective 5-HT2C agonists - addressing issues with hERG inhibition Heather Tye et al	ACS Spring, 21-25 Mar, San Francisco, USA
	Blinded Assessment of Hepatotoxic Pharmaceuticals using Zebrafish MD Aleo et al	SOT, 7-11 March, Salt Lake City, USA
	Electrophysiolocial cardiac safety assessment in drug discovery & development Clemens Moeller et al	BioPhysical Society & Ion Channel Symposium, 20-24 Feb, San Francisco, USA
	Fragment-based GPCR screening: Histamine receptor sub-type specific fragments identified Andreas F Kahrs et al	Screening Europe, 11-12 Feb, Barcelona, Spain
	Biochemical and cellular characterisation of caspase inhibitors for potential treatment of Huntington's Disease Mark Gemkow et al	5th annual conference on HD therapeutics, 5-8 Feb, Palm Springs, USA
	The Development of Potent and Selective Transglutaminase-2 Inhibitors for the Treatment of Huntington’s Disease Michael Prime et al	5th annual conference on HD therapeutics, 5-8 Feb, Palm Springs, USA

February 10, 2012
09:51 AM CET