Publications 2010

2010	Title	Source
	Fragments: past, present and future Mark Whittaker et al	Drug Discovery Today:Technologies 2010, 7 (3): e163-e71
	Using electrophysiology and in silico three-dimensional modeling to reduce human Ether-à-go-go in a histamine H3 receptor antagonist program related gene K⁺ channel Adam Davenport et al	Assay and Drug Development Technologies 2010, 8(6):781-9
	Discovery of substituted benzyl tetrazoles as histamine H3 receptor antagonists Adam Davenport et al	Bioorganic & Medicinal Chemistry Letters 2010, 20(17):5165-69
	Fragment-based discovery and optimization of BACE1 inhibitors James Madden et al	Bioorganic & Medicinal Chemistry Letters 2010, 20(17):5329-33
	An orally bioavailable positive allosteric modulator of the mGlu4 receptor with efficacy in an animal model of motor dysfunction Stephen East et al	Bioorganic & Medicinal Chemistry Letters 2010, 20(16):4901-5
	Keeping the rhythm: hERG and beyond in cardiovascular safety pharmacology Clemens Moeller	Expert Review of Clinical Pharmacology 2010, 3 (3) 321-29
	Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae W Alderton et al	Xenobiotica 2010, 40(8):547-57
	An in Silico Method for Predicting Ames Activities of Primary Aromatic Amines by Calculating the Stabilities of Nitrenium Ions Jörg Bentzien et al	Journal of Chemical Information and Modeling 2010, 50(2):274–97
	A Profiling Platform for the Characterization of Transglutaminase 2 (TG2) Inhibitors Sabine Schärtl et al	Journal of Biomolecular Screening 2010, 15(5):478-87
	Impact of new technologies for cellular screening along the drug value chain Clemens Moeller et al	Drug Discovery Today 2010, 15(9-10):384-90
	mGluR4 positive allosteric modulators with potential for the treatment of Parkinson's disease: WO09010455 Stephen East et al	Expert Opinion in Therapeutic Patents 2010, 20(3):441-5
	The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding Myron A Smith et al	Journal of Biological Chemistry 2010, 285(17):12873-81
	High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand Robert Cheng et al	Protein Science 2010, 19(1):168-73

February 08, 2012
10:47 PM CET