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Spermatech

Through the study of the physiology of sperm motility, more specifically of "rapid swimmers" that cause fertilization, Spermatech have identified biological targets that could be exploited in the development of non-hormonal reversible male contraceptives. On this basis, Evotec and Spermatech have defined a strategy for a tailored drug discovery project.

Evotec will apply its expertise and proprietary technologies in assay development, high-throughput screening and NMR (Nuclear Magnetic Resonance) screening to identify inhibitors of the sperm-specific target protein. The screening will be performed with Evotec's screening library of 250,000 drug-like compounds. Compounds will be identified that reduce sperm motility and will be used in the development of non-hormonal reversible male contraceptives at Spermatech. In addition, compounds that promote target activity may be evaluated as supporters of male fertility.

12 Mar 2008
Spermatech Selects Evotec as Partner for High-Throughput Screening and Lead Discovery